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Friday, 10 February 2012
FDA panel votes against wider use of Amgen drug (Reuters)
[unable to retrieve full-text content]Reuters - An advisory panel on Wednesday recommended that U.S. health regulators reject the use of Amgen Inc's drug Xgeva to delay the spread of prostate cancer to the bone, dimming the chance of a wider use for one of the company's key growth drivers.
Romney intensifies fight for social conservatives (AP) | Space ...
CENTENNIAL, Colo. ? Presidential contender Mitt Romney is fighting to win over social conservatives in Tuesday?s Republican caucuses.
Romney, who previously supported abortion rights, has struggled to convince some cultural conservatives that he?s conservative enough. And rival Rick Santorum hopes to use those voters to score strong finishes in Colorado and Minnesota on Tuesday.
In recent days, Romney has emphasized his social conservative credentials at campaign events and in interviews.
In a radio interview, he said he supported the Susan G. Komen Foundation?s decision to strip funding from Planned Parenthood. Komen later reversed that decision.
In a rally near Denver, he said the Obama administration is forcing religious institutions to distribute ?abortive pills.?
Romney will spend Tuesday meeting with voters in Colorado, before turning to Georgia and Maine.
Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/ap/20120207/ap_on_el_pr/us_romney
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Tiger gets his PGA Tour season off to solid start
Tiger Woods reacts after hitting from the 18th fairway at Spyglass Hill Golf Course during the first round of the Pebble Beach National Pro-Am golf tournament in Pebble Beach, Calif., Thursday, Feb. 9, 2012. (AP Photo/Marcio Jose Sanchez)
Tiger Woods reacts after hitting from the 18th fairway at Spyglass Hill Golf Course during the first round of the Pebble Beach National Pro-Am golf tournament in Pebble Beach, Calif., Thursday, Feb. 9, 2012. (AP Photo/Marcio Jose Sanchez)
Tiger Woods hits from the sixth tee at Spyglass Hill Golf Course during the first round of the AT&T Pebble Beach National Pro-Am golf tournament in Pebble Beach, Calif., Thursday, Feb. 9, 2012. (AP Photo/Marcio Jose Sanchez)
Tiger Woods, right, stands with his amateur partner, Dallas Cowboys NFL football quarterback Tony Romo, at the 18th hole at Spyglass Hill Golf Course during the first round of the Pebble Beach National Pro-Am golf tournament in Pebble Beach, Calif., Thursday, Feb. 9, 2012. (AP Photo/Marcio Jose Sanchez)
Tiger Woods hits from the first fairway at Spyglass Hill Golf Course during the first round of the Pebble Beach National Pro-Am golf tournament in Pebble Beach, Calif., Thursday, Feb. 9, 2012. (AP Photo/Marcio Jose Sanchez)
Tiger Woods hits from the rough toward the fourth hole at Spyglass Hill Golf Course during the first round of the AT&T Pebble Beach National Pro-Am golf tournament in Pebble Beach, Calif., Thursday, Feb. 9, 2012. (AP Photo/Marcio Jose Sanchez)
PEBBLE BEACH, Calif. (AP) ? Tiger Woods felt good about the start at the Pebble Beach National Pro-Am until he looked at the leaderboard.
With six birdies, he opened with a 4-under 68 at Spyglass Hill.
With virtually no wind, and as gorgeous conditions as can be found on the Monterey Peninsula, he was far from the only player who was filling up his scorecard with birdies.
Dustin Johnson, with a small measure of revenge on the third hole at Pebble Beach, made two eagles and saw a third chance at eagle land on the edge of the cup. He wound up with a 9-under 63. Former U.S. Amateur champion Danny Lee also made two eagles at Pebble for a 63.
Over at Monterey Peninsula, Charlie Wi had an outside chance at 59 without even knowing it. Wi wasn't aware the Shore Course was a par 70, so being 8 under through 13 holes didn't get his attention. He made one birdie the rest of the way for a 9-under 61.
They were atop the leaderboard, followed by a record-tying performance by Ken Duke ? 28 on the back nine a Pebble ? that gave him a 64, along with PGA Tour rookie Brian Harman.
It was a perfect day for scenery, and for scoring.
"Especially on courses like this, I can't get too far behind the lead," Woods said. "I know there is some colder weather coming in, but I've got to take advantage of this. The guys are just tearing the course apart with no wind. I think we saw two at 9 (under), two at 8 and a couple of guys at 7. So you've got to take advantage of it.
"Hopefully, in the next two days I can get it going," he said.
Johnson is turning into his generation's "Prince of Pebble." He won the AT&T Pebble Beach National Pro-Am in consecutive years, and then had a three-shot lead at Pebble in the U.S. Open two years ago until he shot 82 in the final round. On the third hole of that round, he hit driver left into the bushes for a lost ball and made double bogey.
On Thursday, he smashed a driver nearly 340 yards over the trees to just short of the green, setting up eagle. Even now, he still thinks about that tee shot in the U.S. Open. Walking off the tee, he said to caddie Bobby Brown, "I could have used that in the U.S. Open."
"Walking off that hole, I told Bob, 'This hole owes me a few more than just that one.'"
Johnson overpowered the par 5s at Pebble Beach, the secret to playing that course well. He had a 6-iron for his second shot at the par-5 second for an easy birdie, holed a 65-foot eagle putt on the sixth hole, got up and down from the bunker just short of the 14th for birdie, then cringed when his 40-foot eagle attempt on the 18th just turned away.
"I thought it was going in," Johnson said. "I was laughing. I made plenty of putts today."
Hunter Mahan, who went from San Diego to Qatar to Pebble Beach, opened with a 65. Phil Mickelson had a 70.
Woods is part of the celebrity rotation, which was at Spyglass Hill. He is on the opposite side of the course from the actors and athletes who command big crowds and lots of cameras, though his gallery was still among the biggest.
He treated them to golf they expected to see from Woods, who has not been at this event in 10 years. He opened on No. 10 by stuffing his approach to tap-in range, and then had a 15-foot eagle putt that he narrowly missed on the next hole.
Woods only missed two fairways, but they cost him ? a bogey on the 13th, failing to make birdie on the par-5 14th. Even so, what really bothered him was his wedge play.
From the middle of the fairway on the 18th, his wedge went over the green, leaving him a tough chip that he nestled down to 3 feet for par. Still, it was a lost opportunity.
One of his two bogeys was sloppy. It came on the short par-4 fourth, with a shallow green set among sand dunes and ice plant at a diagonal angle. Instead of going toward the middle of the green and letting the slope take the ball to the hole, Woods went at the flag. The ball bounced hard over the green and into a sandy patch of dunes, in a foot print.
He did well to blast a wedge some 30 feet past the hole and had a good two-putt from there for bogey.
"I drove it great today," Woods said. "I drove it on a string. I had it going both ways. Unfortunately, going into the greens, I was not very good at all. I had some wedges and hit some awful golf shots. So I'm going to work on that."
Even so, he was in good position.
Woods shot 73 the last time he played Spyglass Hill in 2002, and his average score in six appearances was a 71. He was tied for 15th, a solid start in a tournament that unfolds slowly over three courses, and only three players had a lower score at Spyglass Hill.
Pebble Beach and Spyglass Hill are par 72s. Monterey Peninsula is a par 70.
Wi didn't realize that.
He rolled in plenty of putts from the 20-foot range, and then hit an approach that covered the flag on the 13th hole, the last one that runs along the Pacific Coast and the rolling waves. That put him at 8 under with five holes to play, with 11 under needed for golf's magic number.
"I was looking at the scorecard like, 'What's the par here?' I did not know it was a par 70," Wi said. "That 59 never crossed my mind. Not once."
He was more than happy to settle for a 61, the tournament record at Monterey Peninsula (in its third year as part of the rotation).
"Any time you're shooting 9 under, you're making putts," Wi said. "It was really nice to see the ball go in today."
Woods now heads to Monterey Peninsula, a course he had never played until a practice round this week. Statistically, it was the easiest of the three courses in the opening round, though not by much. All three played about one shot below par.
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Thursday, 9 February 2012
Educating Young Children As A Profession Naples G4
The early childhood education jobs vary. Right from teaching an exclusive or public school, education has undertaken a different perspective and could now be attained in your own home using a completely new solution known as home-schooling. With this said, the matter of a favorable learning environment comes in your thoughts. A child will be needing an environment which is good with regard to learning.
Depending on the age of your child, learning resources such as patterns, toys and games, artificial clays along with moulds are essential on the study room. Significant figures and structures painted with bright colors that can help a child to be able to learn about should decorate the room. This can be a task for a specialist referred to as a children?s psychologist.
A child psychologist is needed for today?s society in order to help make a zone in which a young child associates with education. Seeing that a kid won?t study while bored, specific attention will be put into making a learning area that is enjoyable for the children. A child?s psychologist work is just a tiny part of early childhood education jobs.
Yet another job which falls within early childhood education job opportunities would be the tutor. Each and every school which claims to teach has tutors. The theoretical facet of education must be provided by a person competent for the work. The tutor teaches a child then gives the child a test to find if your kid has perceived the subject. Today?s technology additionally allows kids to try and do tests on a computer program made for that goal. Children learn faster whenever they enjoy whatever they are working on. A qualified tutor makes certain that small children learn.
On today?s fast paced society, young children are frequently left by their parents in day care services. These day care services are usually owned or managed by specialists in early childhood development or has CDA certification and act to some extent as instructors and partially as second parents to those children in the day care center. With a diploma in early childhood education today, you may get your permit to manage a day care facility that attends to young children while their parents work.
Ever since acquiring jobs pose such a difficulty with today?s hard economical conditions, people are getting creative and making new jobs work for them. For instance, using the skills obtained in managing children, you can author children?s storybooks and together with knowledge such as programming, you could design interactive learning applications for children.
Part-time work such as tutoring a child while in your own home for a small price can also be a part of early childhood education job opportunities. Putting aside 2 or 3 hours within a week to teach small kids can be extremely satisfying, not only financially but also psychologically.
Taking time to help show a child the right way to accomplish homework can be a task that?s gratifying by itself. Such tasks could be delegated every now and then to an older person in a day care center whom needs to feel the company of not so small kids. This should be undertaken by someone who will be able to supervise the exercise so as to make certain that both parties that need proper care in this case the aged person and the child interact effectively and also in a helpful manner towards the both. More info here about early childhood education degree online.
Source: http://www.g4naples.org/educating-young-children-as-a-profession/
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We also just finished and addition in Southgate Michigan. The two story Trex deck overlooking Belleville Lake is set to be completed this weekend.
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Source: http://homebaseimprovement.blogspot.com/2012/02/start-your-project-today.html
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Wednesday, 8 February 2012
Gay and Lesbian Friendly Yellow Pages Directory ? GayFriendlyBiz ...
The federal court ruling Tuesday that Proposition 8, California?s ban on gay marriage, is unconstitutional will not lead to an immediate rush for marriage licenses across?California, say?legal analysts as well as same-sex couples who have been waiting for the court?s decision.
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The main reason is the stay on the decision, which prevents same-sex couples from marrying in order to avoid having to undo the marriages if another court were to overrule the decision. This actually happened in 2008, when 18,000 couples got married after the state Supreme Court ruled that same-sex marriage was legal, only to have voters pass Prop. 8 five months later. Their legal status remains in question.
But the general uncertainty over the status of gay marriage nationwide is also a factor for some couples.?
RECOMMENDED: Gay marriage in the US: seven ways states differ?
Long Beach?residents Kimberlee Ward and Anne Albertine, who have had a domestic partnership certificate for seven years ? and who have a 13-month-old daughter, Ava ? say they are?not going to get married until the US Supreme Court weighs in.
?We are waiting until it is fully recognized on the federal and state levels,? says Ms. Ward, director of admissions at an elementary school. ?We don?t want to be married one day and then be declared illegal the next, or be considered differently for federal and state taxes.?
Ward is Ava?s birth mother, but the couple has given their daughter Ms. Albertine?s last name, to give Albertine more legal rights. The couple has not gone through adoption procedures.
?We love the idea that now Ava can see us in the same light as the parents of her friends and understand our marriage and relationship is just as valuable and loving as any other married couple,? says Ward.
According to the an analysis by the Williams Institute, which compiles statistics countrywide on sexual orientation and gender identity, nearly 100,000 same-sex couples live in California, raising more than 30,000 children under age 18. Based on how many couples have gotten married in other states upon the legalization of same-sex marriage, the institute predicts that more than 24,000 couples are likely to marry within three years of the stay being lifted, or a Supreme Court ruling in their favor.
Opponents of gay marriage called the ruling by the US Ninth Circuit Court of Appeals in San Francisco a mistake.
?Today?s decision was disappointing but not surprising, coming from the most liberal Circuit Court in the country,? wrote?Family Research Council President Tony Perkins?in a statement. ?This Hollywood-funded lawsuit, which seeks to impose?San Francisco?values on the entire country, may eventually reach the Supreme Court. This is not about constitutional governance but the insistence of a group of activists to?force their will on their fellow citizens.?
For?San Francisco?couple Lorie Nachlis and Abby Abinanti, who have been in a committed relationship for 13 years, anything other than marriage is a second-class arrangement. They have?rejected the idea of a legal domestic partnership.?
?Within seconds of this decision, my son texted me to say, ?Now are you getting married?? ? says Ms. Nachlis, who is divorced from a heterosexual marriage. ?We have a lot of extended family for who this will give a great feeling of stability.?
With a legal background as divorce lawyer, Nachlis thinks the stay will be in effect until the US Supreme Court rules or refuses to take the case. But because she is nearing 60, Nachlis says she may be inclined to go to another state to get married.
?This age issue hit home a couple weeks ago when I was hospitalized, and it occurred to me that I don?t have a surviving spouse, and also who would be making decisions for me,? says Nachlis. ?I really, really want to get married in California, but this moment made me realize maybe it?s time to get married in Iowa.?
Indeed, even beyond court rulings, the issue of gay marriage is in flux in California.?
?This is the time to celebrate this incredible victory,? said Eric Harrison, interim executive president of Love Honor Cherish, an anti-Prop. 8 organization.
But if it is not clear by spring whether or not same-sex couples can legally wed,?his group is still planning to?collect signatures for an 2012 ballot initiative to overthrow Prop. 8.
He says: ?It?s obviously a lingering question, whether gays and lesbians can get married now or how long this stay will be in place.??
RECOMMENDED: Gay marriage in the US: seven ways states differ?
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Article source: http://www.csmonitor.com/USA/Justice/2012/0207/Prop.-8-struck-down-Will-California-s-gay-couples-flock-to-the-altar
Tags: gay, glbt, lesbian, lgbt
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Discovery uses 'fracture putty' to repair broken bone in days
ScienceDaily (Feb. 7, 2012) ? Broken bones in humans and animals are painful and often take months to heal. Studies conducted in part by University of Georgia Regenerative Bioscience Center researchers show promise to significantly shorten the healing time and revolutionize the course of fracture treatment.
"Complex fractures are a major cause of amputation of limbs for U.S. military men and women," said Steve Stice, a Georgia Research Alliance Eminent Scholar, animal and dairy scientist in the UGA College of Agricultural and Environmental Sciences and director of the UGA Regenerative Bioscience Center.
"For many young soldiers, their mental health becomes a real issue when they are confined to a bed for three to six months after an injury," he said. "This discovery may allow them to be up and moving as fast as days afterward."
Stice is working with Dr. John Peroni to develop a fast bone healing process. "This process addresses both human and veterinary orthopedic needs," said Peroni, an associate professor of large animal surgery in the UGA College of Veterinary Medicine and a member of the RBC.
Peroni and Stice are leading a large animal research project funded by the U.S. Department of Defense. The project includes scientists and surgeons from the Baylor University College of Medicine, Rice University and the University of Texas, who conducted the early studies.
Engineering new bone
"Healing of critical-size defects is a major challenge to the orthopedic research community," Peroni said. "Large-bone defects must be stabilized and necessitate technologies that induce rapid bone formation in order to replace the missing tissue and allow the individual to return to rapid function. To date, no single material can suffice."
The group they lead is a multidiscipline and multi-institutional group actively working on bone tissue engineering.
"Our group has been working productively together on numerous projects through the last several years," Stice said, "So, a collegial relationship and successful collaborative working relationship is already established."
Between 2009 and 2011, the collaborations received a $1.4 million grant from the DOD for the use of stem cells in fracture healing to be tested in sheep.
"In our experiences with large animal models, following the guidelines established by our animal care and use committee," Stice said, "we have been successful in formulating a product that contains mesenchymal stem cells and allows them to survive in the environment of the fracture long enough to elicit the rapid formation of new bone."
This year, the group showed bone can be generated in sheep in less than four weeks. The speed in which bone is formed is one of the truly unique features of this study.
Fracture putty
To start the bone regeneration process, the RBC used adult stem cells that produce a protein involved in bone healing and generation. They then incorporated them into a gel, combining the healing properties into something Stice calls "fracture putty."
With Peroni's assistance, the Houston-based team used a stabilizing device and inserted putty into fractures in rats. Video of the healed animals at two weeks shows the rats running around and standing on their hind legs with no evidence of injury. The RBC researchers are testing the material in pigs and sheep, too.
"The small-animal work has progressed, and we are making good progress in large animals," he said.
More work is needed to get to human medical trials, but the threat of losing federal funding for biomedical work through the DOD means they will have to find new ways to fund the project.
Next steps
"The next step is to show that we can rapidly and consistently heal fractures in a large animal," Peroni said, "then to convert it to clinical cases in the UGA [College of Veterinary Medicine] clinics where clinicians treat animals with complex fractures all the time."
Once they have something that works for animals, it will be passed over to the DOD for human use.
Peroni, who is chairman of the North American Veterinary Regenerative Medicine Association, is hopeful this material will be promoted to the veterinary and human medical fields through the educational efforts of NAVRMA and the RBC.
However, the RBC isn't the only group working on a faster fix for broken bones.
"Our approach is biological with the putty," Stice said. "Other groups are looking at polymers and engineering approaches like implants and replacements which may eventually be combined with our approach. We are looking at other applications, too, using this gel, or putty, to improve spinal fusion outcomes."
One of the best hopes for the fracture putty is in possible facial cranial replacements, an injury often seen on the battlefield.
The project ends in mid-2012. "By then we are to deliver the system to the DOD," Stice said.
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The above story is reprinted from materials provided by University of Georgia. The original article was written by Faith Peppers.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://www.sciencedaily.com/releases/2012/02/120207193407.htm
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