Thursday, 2 May 2013

First Person: For Me, PTSD Is a Life Sentence

May 1 (Reuters) - Post position for Saturday's 139th Kentucky Derby at Churchill Downs after Wednesday's draw (listed as barrier, HORSE, jockey, trainer) 1. BLACK ONYX, Joe Bravo, Kelly Breen 2. OXBOW, Gary Stevens, D. Wayne Lukas 3. REVOLUTIONARY, Calvin Borel, Todd Pletcher 4. GOLDEN SOUL, Robby Albarado, Dallas Stewart 5. NORMANDY INVASION, Javier Castellano, Chad Brown 6. MYLUTE, Rosie Napravnik, Tom Amoss 7. GIANT FINISH, Jose Espinoza, Tony Dutrow 8. GOLDENCENTS, Kevin Krigger, Doug O'Neill 9. OVERANALYZE, Rafael Bejarano, Todd Pletcher 10. PALACE MALICE, Mike Smith, Todd Pletcher 11. ...

Source: http://news.yahoo.com/first-person-ptsd-life-sentence-205900850.html

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New guide details steps from A-to-Z for preserving biological evidence

New guide details steps from A-to-Z for preserving biological evidence [ Back to EurekAlert! ] Public release date: 1-May-2013
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Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)

A new handbook by the National Institute of Standards and Technology (NIST) and the Department of Justice's National Institute of Justice (NIJ) provides forensic laboratories, law enforcement agencies and the judicial system with state-of-the-art guidelines and recommended best practices for preserving biological evidence so that it is available at any time to solve "cold cases," confirm the guilt of criminals or exonerate the innocent.

Biological evidence refers to two types of evidence commonly recovered from crime scenes or collected during criminal investigations: samples of biological materialblood, semen and other bodily fluids; hair; tissue; bones and teethor items containing biological material such as a bloody T-shirt. The Biological Evidence Preservation Handbook: Best Practices for Evidence Handlers (NIST Interagency/Internal Report 7928) is designed to help ensure that this evidence has been properly stored to avoid contamination, premature destruction or degradation, and accurately tracked to prevent loss. It was authored and edited by the Technical Working Group on Biological Evidence Preservation, a group of 20 experts from various forensic, law enforcement and scientific disciplines, as well as legal scholars, medical personnel and representatives of relevant professional organizations.

The handbook is divided into five main sections that explain the issues, offer guidelines and make recommendations related to:

  • Retentionidentifying what biological evidence should be kept and for how long;
  • Safe handlingincluding the use of protective equipment, the management of spills or accidents, and methods for properly disposing waste;
  • Packaging and storingoutlining the conditions for storage and how to properly package biological evidence to maintain its integrity;
  • Chain of custody and trackinga review of the different evidence-tracking methods available and procedures for improving all aspects of chain-of-custody recordkeeping; and
  • Dispositionsummarizing the best practices for disposing of biological evidence once retention is no longer required by law.

While most of its recommendations concern the physical storing, preserving and tracking of evidence at a specific storage facility, the handbook also covers transferring material between a storage facility and other locations and discusses how evidence should be handled at these different sites.

Complementing the five main sections of the handbook are a summary of all recommendations made, a table showing the functions and capabilities of evidence tracking and management systems, a state-by-state listing of evidence retention laws, a sample chain-of-custody report and a glossary.

###

NISTIR 7928 may be downloaded at http://nvlpubs.nist.gov/nistpubs/ir/2013/NIST.IR.7928.pdf. Print copies are available upon request from the National Criminal Justice Reference Service at https://www.ncjrs.gov.


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New guide details steps from A-to-Z for preserving biological evidence [ Back to EurekAlert! ] Public release date: 1-May-2013
[ | E-mail | Share Share ]

Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)

A new handbook by the National Institute of Standards and Technology (NIST) and the Department of Justice's National Institute of Justice (NIJ) provides forensic laboratories, law enforcement agencies and the judicial system with state-of-the-art guidelines and recommended best practices for preserving biological evidence so that it is available at any time to solve "cold cases," confirm the guilt of criminals or exonerate the innocent.

Biological evidence refers to two types of evidence commonly recovered from crime scenes or collected during criminal investigations: samples of biological materialblood, semen and other bodily fluids; hair; tissue; bones and teethor items containing biological material such as a bloody T-shirt. The Biological Evidence Preservation Handbook: Best Practices for Evidence Handlers (NIST Interagency/Internal Report 7928) is designed to help ensure that this evidence has been properly stored to avoid contamination, premature destruction or degradation, and accurately tracked to prevent loss. It was authored and edited by the Technical Working Group on Biological Evidence Preservation, a group of 20 experts from various forensic, law enforcement and scientific disciplines, as well as legal scholars, medical personnel and representatives of relevant professional organizations.

The handbook is divided into five main sections that explain the issues, offer guidelines and make recommendations related to:

  • Retentionidentifying what biological evidence should be kept and for how long;
  • Safe handlingincluding the use of protective equipment, the management of spills or accidents, and methods for properly disposing waste;
  • Packaging and storingoutlining the conditions for storage and how to properly package biological evidence to maintain its integrity;
  • Chain of custody and trackinga review of the different evidence-tracking methods available and procedures for improving all aspects of chain-of-custody recordkeeping; and
  • Dispositionsummarizing the best practices for disposing of biological evidence once retention is no longer required by law.

While most of its recommendations concern the physical storing, preserving and tracking of evidence at a specific storage facility, the handbook also covers transferring material between a storage facility and other locations and discusses how evidence should be handled at these different sites.

Complementing the five main sections of the handbook are a summary of all recommendations made, a table showing the functions and capabilities of evidence tracking and management systems, a state-by-state listing of evidence retention laws, a sample chain-of-custody report and a glossary.

###

NISTIR 7928 may be downloaded at http://nvlpubs.nist.gov/nistpubs/ir/2013/NIST.IR.7928.pdf. Print copies are available upon request from the National Criminal Justice Reference Service at https://www.ncjrs.gov.


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/nios-ngd050113.php

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University of Maryland School of Medicine researchers find potential novel treatment for influenza

University of Maryland School of Medicine researchers find potential novel treatment for influenza [ Back to EurekAlert! ] Public release date: 1-May-2013
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Contact: Karen Robinson
krobinson@som.umaryland.edu
410-706-7590
University of Maryland Medical Center

Scientists pursue new therapies as deadly H7N9 flu spreads in China

An experimental drug has shown promise in treating influenza, preventing lung injury and death from the virus in preclinical studies, according to University of Maryland School of Medicine researchers publishing in the journal Nature on May 1. The scientists found that a drug called Eritoran can protect mice from death after they have been infected with a lethal dose of influenza virus. The potential value of this drug as single therapy or in combination with antivirals is further supported by previous research that found that it is safe for use in humans. The findings are of particular interest to scientists now that the latest deadly strain of flu, H7N9, is spreading in China 82 people in China had been infected with the new strain of flu virus as of April 26, and 17 had died.

Previous scientific studies have revealed that acute lung injury caused by the influenza virus is the result of an immune reaction mediated by a protein called Toll-like receptor 4 (TLR4). Senior author Stefanie Vogel, Ph.D., Professor of Microbiology and Immunology and Medicine at the University of Maryland, and colleagues previously demonstrated that mice that lack the ability to signal through TLR4 are highly refractory to influenza-induced lethality. In their new study, they extend these findings by showing that Eritoran a synthetic inhibitor of TLR4, originally developed by Eisai Inc. for treatment of sepsis improved clinical symptoms and prevented death when administered up to six days after infection with the influenza virus. Existing antiviral medications must be administered within two days of infection to be optimally effective.

Annual influenza epidemics are estimated to result in 3 million to 5 million cases of severe illness and 250,000 to 500,000 deaths yearly worldwide. The virus is continually evolving and new variants give rise to seasonal outbreaks. Increasing resistance to existing antiviral therapies and the short time-frame in which these agents are effective highlight the critical need for new treatments, such as Eritoran.

"Currently, vaccines and antiviral medications are the two main approaches to preventing influenza," says Dr. Vogel. "Problems associated vaccine development may limit efficacy and/or vaccine availability. In addition, people suffering from influenza may not go to the doctor or to the emergency room in time for the antivirals to be effective. Also, as the flu adapts to resist existing treatments, we are in search of new therapies to save lives and prevent severe illness. Our research seems to show that Eritoran could provide doctors with a new tool in their flu-fighting toolbox, as well as several more days to treat the sickest of patients successfully . More basic research is needed, but we are hopeful that this medication could one day change the way that we treat severe influenza and possibly other pathogens that cause disease by a similar mechanism."

###


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


University of Maryland School of Medicine researchers find potential novel treatment for influenza [ Back to EurekAlert! ] Public release date: 1-May-2013
[ | E-mail | Share Share ]

Contact: Karen Robinson
krobinson@som.umaryland.edu
410-706-7590
University of Maryland Medical Center

Scientists pursue new therapies as deadly H7N9 flu spreads in China

An experimental drug has shown promise in treating influenza, preventing lung injury and death from the virus in preclinical studies, according to University of Maryland School of Medicine researchers publishing in the journal Nature on May 1. The scientists found that a drug called Eritoran can protect mice from death after they have been infected with a lethal dose of influenza virus. The potential value of this drug as single therapy or in combination with antivirals is further supported by previous research that found that it is safe for use in humans. The findings are of particular interest to scientists now that the latest deadly strain of flu, H7N9, is spreading in China 82 people in China had been infected with the new strain of flu virus as of April 26, and 17 had died.

Previous scientific studies have revealed that acute lung injury caused by the influenza virus is the result of an immune reaction mediated by a protein called Toll-like receptor 4 (TLR4). Senior author Stefanie Vogel, Ph.D., Professor of Microbiology and Immunology and Medicine at the University of Maryland, and colleagues previously demonstrated that mice that lack the ability to signal through TLR4 are highly refractory to influenza-induced lethality. In their new study, they extend these findings by showing that Eritoran a synthetic inhibitor of TLR4, originally developed by Eisai Inc. for treatment of sepsis improved clinical symptoms and prevented death when administered up to six days after infection with the influenza virus. Existing antiviral medications must be administered within two days of infection to be optimally effective.

Annual influenza epidemics are estimated to result in 3 million to 5 million cases of severe illness and 250,000 to 500,000 deaths yearly worldwide. The virus is continually evolving and new variants give rise to seasonal outbreaks. Increasing resistance to existing antiviral therapies and the short time-frame in which these agents are effective highlight the critical need for new treatments, such as Eritoran.

"Currently, vaccines and antiviral medications are the two main approaches to preventing influenza," says Dr. Vogel. "Problems associated vaccine development may limit efficacy and/or vaccine availability. In addition, people suffering from influenza may not go to the doctor or to the emergency room in time for the antivirals to be effective. Also, as the flu adapts to resist existing treatments, we are in search of new therapies to save lives and prevent severe illness. Our research seems to show that Eritoran could provide doctors with a new tool in their flu-fighting toolbox, as well as several more days to treat the sickest of patients successfully . More basic research is needed, but we are hopeful that this medication could one day change the way that we treat severe influenza and possibly other pathogens that cause disease by a similar mechanism."

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/uomm-uom050113.php

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The biology behind binge eating

May 1, 2013 ? Female rats are much more likely to binge eat than male rats, according to new research that provides some of the strongest evidence yet that biology plays a role in eating disorders.

The study, by Michigan State University scientists, is the first to establish sex differences in rates of binge eating in animals and has implications for humans. Binge eating is one of the core symptoms of most eating disorders, including bulimia nervosa and the binge/purge subtype of anorexia nervosa, and females are four to 10 times more likely than males to have an eating disorder.

"Most theories of why eating disorders are so much more prevalent in females than males focus on the increased cultural and psychological pressure that girls and women face," said Kelly Klump, lead author and professor of psychology. "But this study suggests that biological factors likely contribute as well, since female rats do not experience the psychosocial pressures that humans do, such as pressures to be thin."

Klump and colleagues ran a feeding experiment with 30 female and 30 male rats over a two-week period, replacing the rodents' food pellets periodically with vanilla frosting. They found that the rate of binge eating "proneness" (i.e., the tendency to consume the highest amount of frosting across all feeding tests) was up to six times higher in female as compared to male rats.

The tendency to binge eat may be related to the brain's natural reward system, or the extent to which someone likes and seeks reward, Klump said. The MSU researchers currently are testing the rats to see if female brains are more sensitive and/or responsive to rewarding stimuli (e.g., high-fat, high-sugar food) and the chemicals that trigger reward behavior.

The answers could ultimately help improve therapy -- both counseling and medications -- for those with eating disorders.

"This research suggests there is probably a biological difference between males and females that we need to explore to understand risk factors and mechanisms," Klump said.

The study is published online in the International Journal of Eating Disorders. Klump's co-authors are Cheryl Sisk, psychology professor, and graduate students Sarah Racine and Britny Hildebrandt.

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The above story is reprinted from materials provided by Michigan State University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Kelly L. Klump, Sarah Racine, Britny Hildebrandt, Cheryl L. Sisk. Sex differences in binge eating patterns in male and female adult rats. International Journal of Eating Disorders, 2013; DOI: 10.1002/eat.22139

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/ccUxlKfnpzc/130501101304.htm

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Wednesday, 1 May 2013

Deep, detailed image of distant universe

Apr. 30, 2013 ? Staring at a small patch of sky for more than 50 hours with the ultra-sensitive Karl G. Jansky Very Large Array (VLA), astronomers have for the first time identified discrete sources that account for nearly all the radio waves coming from distant galaxies. They found that about 63 percent of the background radio emission comes from galaxies with gorging black holes at their cores and the remaining 37 percent comes from galaxies that are rapidly forming stars.

"The sensitivity and resolution of the VLA, following its decade-long upgrade, made it possible to identify the specific objects responsible for nearly all of the radio background emission coming from beyond our own Milky Way Galaxy," said Jim Condon, of the National Radio Astronomy Observatory (NRAO). "Before we had this capability, we could not detect the numerous faint sources that produce much of the background emission," he added.

Previous studies had measured the amount of radio emission coming from the distant Universe, but had not been capable of attributing all the radio waves to specific objects. In earlier observations, emission from two or more faint objects often was blurred or blended into what appeared to be a single, stronger source of radio waves.

"Advancing technology has revealed more and more of the Universe to us over the past few decades, and our study shows individual objects that account for about 96 percent of the background radio emission coming from the distant Universe," Condon said. "The VLA now is a million times more sensitive than the radio telescopes that made landmark surveys of the sky in the 1960s," he added.

In February and March of 2012, Condon and his colleagues studied a region of sky that previously had been observed by the original, pre-upgrade, VLA, and by the Spitzer space telescope, which observes infrared light. They carefully analyzed and processed their data, then produced an image that showed the individual, radio-emitting objects within their field of view.

Their field of view, in the constellation Draco, encompassed about one-millionth of the whole sky. In that region, they identified about 2,000 discrete radio-emitting objects. That would indicate, the scientists said, that there are about 2 billion such objects in the whole sky. These are the objects that account for 96 percent of the background radio emission. However, the researchers pointed out, the remaining 4 percent of the radio emission could be coming from as many as 100 billion very faint objects.

Further analysis allowed the scientists to determine which of the objects are galaxies containing massive central black holes that are actively consuming surrounding material and which are galaxies undergoing rapid bursts of star formation. Their results indicate that, as previously proposed, the two types of galaxies evolved at the same rate in the early Universe.

"What radio astronomers have accomplished over the past few decades is analogous to advancing from the early Greek maps of the world that showed only the Mediterranean basin to the maps of today that show the whole world in exquisite detail," Condon said.

Condon worked with William Cotton, Edward Fomalont, Kenneth Kellermann, and Rick Perley of NRAO; Neal Miller of the University of Maryland; and Douglas Scott, Tessa Vernstrom, and Jasper Wall of the University of British Columbia. The researchers published their work in the Astrophysical Journal.

The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

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Story Source:

The above story is reprinted from materials provided by National Radio Astronomy Observatory.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/mTyk6s_jXfw/130430105948.htm

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Tuesday, 30 April 2013

Court seeks 'Stand Your Ground' answer from Goerge Zimmerman

By Barbara Liston

ORLANDO (Reuters) - Prosecutors in Florida want George Zimmerman to state publicly at a court hearing on Tuesday whether he will pursue his immunity defense in the 2012 shooting death of teenager Trayvon Martin on the basis of the state's "Stand Your Ground" law, or waive his right to use it.

Prosecutors asked Judge Debra Nelson in a motion to remind Zimmerman "that should defendant in fact wish to waive any pre-trial immunity challenge under this statute, he may not attempt to do so later, particularly once trial has commenced."

Zimmerman will attend Tuesday's hearing, according to his lawyer, Mark O'Mara. However, O'Mara told Reuters he hadn't decided what he will do if the judge tries to question his client.

"I know the state would like to have that information, it seems. I don't feel compelled to advise anybody of my strategy in this case," O'Mara said.

Zimmerman goes on trial June 10 on a second-degree murder charge for shooting Martin after prosecutors say he profiled and confronted the unarmed black teenager, despite a police dispatcher instructing him not to do so.

Zimmerman, 29, was a neighborhood watch volunteer at the time and Martin was walking back to a town home in the gated community in Sanford, Florida, with snacks to eat while watching a televised basketball game in February last year.

O'Mara has talked publicly about pursuing immunity for Zimmerman under Florida's controversial "Stand Your Ground" statute, which bars prosecution of someone who is in fear of his life and shoots rather than retreats. O'Mara canceled a scheduled hearing earlier this month to make the case, but told Reuters he believes he has the right to raise the immunity defense at any time during the trial.

"If you can convince someone, a judge, by preponderance of evidence that you acted in self defense, then you're immune, and that can happen however it happens," O'Mara said.

Prosecutors want to pin Zimmerman down on the record over waiving his right to pursue immunity in order to pre-empt the possibility that he might try to revive it after trial if he is found guilty, according to the motion. O'Mara said it would be difficult to raise the issue post-conviction.

Nelson also will hear a defense request to unseal a settlement between Martin's parents and the homeowner's association at The Retreat at Twin Lakes subdivision where Martin was killed.

The association's insurance company at one point offered its policy limit of $1 million to the family, according to correspondence between the insurance company and association attached to the motion. The defense argues that the jury should be able to consider the financial interest of potential witnesses in the case.

(Editing by David Adams and Christopher Wilson)

Source: http://news.yahoo.com/florida-teenagers-shooter-faces-deadline-court-110517464.html

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Photo artist draws on tragic current events and kids for inspiration

OTTAWA - For Picasso's masterpiece Guernica, it was the German bombing of a Spanish town. For Ottawa art photographer Jonathan Hobin's Twins, it was 9/11.

Current events have always inspired art and Hobin's latest instalment in his controversial series "In the Playroom" is an arresting modern example.

Each of his photos depicts children at play re-enacting tragic public events.

Hobin, 33, has portrayed familiar stories, such as a Halloween-inspired Abu Ghraib prison scene, a portrait of the late North Korean dictator Kim Jong il, and JonBen?t Ramsay dressed in a pageant gown, among others.

He says the child models in his photographs are unpaid volunteers, and are either the children of friends and family, or models from agencies.

"I definitely would never have photographed a child unless I fully communicated what I was going to do," he said in an interview.

Parents "had to believe in what I was doing if I was going to photograph their child."

The idea for the series came after Hobin witnessed the repeated and unforgettable images of the planes striking the World Trade Center towers on 9/11.

"I started to think: 'I'm an adult and I can kind of handle what that means,'" he said.

"But with someone who is not as equipped as I am with problem-solving or just life experiences, how are they going to see that sort of thing? How are they going to comprehend what that means?"

By portraying children acting out headline-grabbing news events, Hobin explores how young minds deal with the unsettling side of the modern media-scape.

"It goes back to this whole notion that children always have incorporated things they see in popular culture into their play," he said.

"In fact, science shows that children need to physically re-enact things in order to process them. There's a tactile nature to their minds."

In one of Hobin's newest photographs, GOT HIM!, a marine with a toy gun shoots Osama Bin Laden in a messy ketchup-blood scene beside a kitchen fridge.

Hobin says his work has been polarizing. In between critical praise and gifts from fans, he's received death threats and accusations of pedophilia.

"It was quite a surprise, but I'd rather have people be excited and energetic about what I'm doing than really blas? about the whole thing."

Asked whether he would depict the recent Boston Marathon bombings, Hobin said such events need time to play out in the culture before he can consider reflecting the stories visually.

"It took probably about six or seven years before I did the 9/11 attacks. You kind of let the dust settle and see how it plays out," he said.

He says that while kids use play as a tool to process, it also reflects their emotional resilience versus the fragility of adulthood.

"They might be better equipped to survive the emotional side of what's happening at this age than we are as adults."

Starting Thursday, 17 of Hobin's images from "In the Playroom" will be released as a feature exhibition in Toronto's Contact photography festival at the Gladstone Hotel, in partnership with the Patrick Mikhail Gallery.

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On the web: www.jhobin.com

Source: http://www.montrealgazette.com/entertainment/Photo+artist+draws+tragic+current+events+kids/8306764/story.html

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